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proinflammatory baseline, genetic liability, or frequent energy-dense meals amplify and prolong the response ( 109 , 110 )
FDA-approved GLP-1 receptor agonists include semaglutide (Wegovy, Ozempic), tirzepatide (Mounjaro, Zepbound), liraglutide (Saxenda, Victoza), dulaglutide (Trulicity), and exenatide (Byetta, Bydureon)
Recognition of differences leads to more effective assistance strategies
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In September 2024, Terns Pharmaceuticals announced positive results from its Phase 1 clinical trial for TERN-601, a once-daily oral GLP-1 receptor agonist aimed at treating obesity
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